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In a nut­shell (sup­pos­ing you start from scratch):

$ sudo apt-get install wine cabextract
 
$ rm .wine/drive_c/Program Files/Microchip -rf (to remove anything that failed)
 
$ wget http://kegel.com/wine/winetricks
 
$ sh winetricks vcrun6
 
$ wget http://ww1.microchip.com/downloads/en/DeviceDoc/mp760a.zip
 
$ unzip mp760a.zip -d microchip
 
$ wine Install_MP760a.exe
 
$ wineserver -k (to get rid of splash screen at the end of install)
 
$ sh winetricks dcom98
 
$ wine .wine/drive_c/Program Files/Microchip/MPLAB IDE/Core/MPLAB.exe

MPLAB 7.60 under Wine

I can’t tell yet if ICD2 is sup­ported with this setup… Stay tuned.

Here’s the orig­i­nal ref­er­ence that helped me get­ting out of a splash screen hang­ing problem:

http://www.nabble.com/-Bug-8407–MPLab-7.60-hangs-at-splash-screen-t3765354.html